Annex 2 Classification and Labeling Summary Tables
The below tables should function as a reference when labeling chemicals for identification.
Hazard category | Criteria | Hazard communication elements |
---|---|---|
Unstable explosives | According to the results of the test in Part I of the Manual of Tests and Criteria, UN Recommendations on the Transport of Dangerous Goods. |
Symbol: Signal word: Danger |
Division 1.1 | According to the results of the test in Part I of the Manual of Tests and Criteria, UN Recommendations on the Transport of Dangerous Goods. | Symbol: ![]() Signal word: Danger Hazard statement: Explosive; mass explosion hazard |
Division 1.2 | According to the results of the test in Part I of the Manual of Tests and Criteria, UN Recommendations on the Transport of Dangerous Goods. | Symbol: ![]() Signal word: Danger Hazard statement: Explosive; severe projection hazard |
Division 1.3 | According to the results of the test in Part I of the Manual of Tests and Criteria, UN Recommendations on the Transport of Dangerous Goods. | Symbol: ![]() Signal word: Danger Hazard statement: Explosive; fire, blast or projection hazard |
Division 1.4 | According to the results of the test in Part I of the Manual of Tests and Criteria, UN Recommendations on the Transport of Dangerous Goods. | Symbol: ![]() Signal word: Warning Hazard statement: Fire or projection hazard |
Division 1.5 | According to the results of the test in Part I of the Manual of Tests and Criteria , UN Recommendations on the Transport of Dangerous Goods. | Symbol: 1.5 Signal word: Danger Hazard statement: May mass explode in fire |
Division 1.6 | According to the results of the test in Part I of the Manual of Tests and Criteria, UN Recommendations on the Transport of Dangerous Goods. | Symbol: 1.6 No signal word or hazard statement |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | Gases and gas mixtures, which at 20 °C and a standard pressure of 101.3 kPa: (a) are ignitable when in a mixture of 13% or less by volume in air; or (b) have a flammable range with air of at least 12 percentage points regardless of the lower flammable limit. |
Symbol: ![]() Signal word: Danger Hazard statement: Extremely flammable gas |
2 | Gases or gas mixtures, other than those of Category 1, which, at 20 °C and a standard pressure of 101.3 kPa, have a flammable range while mixed in air | Symbol: N/A Signal word: Warning Hazard statement: Flammable gas |
A (chemically unstable gases) | Flammable gases which are chemically unstable at 20 °C and a standard pressure of 101.3 kPa | No additional symbol or signal word Hazard statement: May react explosively even in the absence of air |
B (chemically unstable gases) | Flammable gases which are chemically unstable at a temperature greater than 20 °C and/or a pressure greater than 101.3 kPa | No additional symbol or signal word Hazard statement: May react explosively even in the absence of air at elevated pressure and/or temperature |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | On the basis of its ingredients, of its chemical heat of combustion and, if applicable, of the results of the foam test (for foam aerosols) and of the ignition distance test and enclosed space test (for spray aerosols) (see decision logic under 2.3.4.1 in Chapter 2.3) | Symbol: ![]() Signal word: Danger Hazard statement: Extremely flammable aerosol. Pressurized container, may burst if heated |
2 | On the basis of its ingredients, of its chemical heat of combustion and, if applicable, of the results of the foam test (for foam aerosols) and of the ignition distance test and enclosed space test (for spray aerosols) (see decision logic under 2.3.4.1 in Chapter 2.3) | Symbol: ![]() Signal word: Warning Hazard statement: Flammable aerosol. Pressurized container, may burst if heated |
3 | On the basis of its ingredients, of its chemical heat of combustion and, if applicable, of the results of the foam test (for foam aerosols) and of the ignition distance test and enclosed space test (for spray aerosols) (see decision logic under 2.3.4.1 in Chapter 2.3) | No Symbol Signal word: Warning Hazard statement: Pressurized container, may burst if heated |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | Any gas which may, generally by providing oxygen, cause or contribute to the combustion of other material more than air does | Symbol: ![]() Signal word: Danger Hazard statement: May cause or intensify fire; oxidizer |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
Compressed gas | A gas, which when packaged under pressure is entirely gaseous at -50 °C; including all gases with a critical temperature ≤ -50 °C | Symbol: ![]() Signal word: Warning Hazard statement: Contains gas under pressure; may explode if heated |
Liquefied gas | A gas which when packaged under pressure, is partially liquid at temperatures above -50 °C. A distinction is made between: (a) High pressure liquefied gas: a gas with a critical temperature between –50 °C and +65 °C; and (b) Low pressure liquefied gas: a gas with a critical temperature above +65 °C |
Symbol: ![]() Signal word: Warning Hazard statement: Contains gas under pressure; may explode if heated |
Refrigerated liquefied gas | A gas which when packaged is made partially liquid because of its low temperature | Symbol: ![]() Signal word: Warning Hazard statement: Contains refrigerated gas; may cause cryogenic burns or injury |
Dissolved gas | A gas which when packaged under pressure is dissolved in a liquid phase solvent | Symbol: ![]() Signal word: Warning Hazard statement: Contains gas under pressure; may explode if heated |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | Flash point < 23 °C and initial boiling point ≤ 35 °C | Symbol: ![]() Signal word: Danger Hazard statement: Extremely flammable liquid and vapor |
2 | Flash point < 23 °C and initial boiling point >35 °C | Symbol: ![]() Signal word: Danger Hazard statement: Highly flammable liquid and vapor |
3 | Flash point ≥ 23 °C and ≤ 60 °C | Symbol: ![]() Signal word: Warning Hazard statement: Flammable liquid and vapor |
4 | Flash point > 60 °C and ≤ 93 °C | No Symbol Signal word: Warning Hazard statement: Combustible liquid |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | Burning rate test: Substances and mixtures other than metal powders: (a) wetted zone does not stop fire and (b) burning time < 45 s or burning rate > 2.2 mm/s Metal powders: - burning time ≤ 5 min |
Symbol: ![]() Signal word: Danger Hazard statement: Flammable solid |
2 | Burning rate test: Substances and mixtures other than metal powders: (a) wetted zone stops the fire for at least 4 min and (b) burning time < 45 s or burning rate > 2.2 mm/s Metal powders: - burning time > 5 min and ≤ 10 min |
Symbol:![]() Signal word: Warning Hazard statement: Flammable solid |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
Type A | According to the results of tests in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part II and the application of the decision logic under 2.8.4.1 in Chapter 2.8. | Symbol: ![]() Signal word: Danger Hazard statement: Heating may cause an explosion |
Type B | According to the results of tests in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part II and the application of the decision logic under 2.8.4.1 in Chapter 2.8. | Symbols: ![]() ![]() Signal word: Danger Hazard statement: Heating may cause a fire or explosion |
Type C and D | According to the results of tests in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part II and the application of the decision logic under 2.8.4.1 in Chapter 2.8. | Symbol: ![]() Signal word: Danger Hazard statement: Heating may cause a fire |
Type E and F | According to the results of tests in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part II and the application of the decision logic under 2.8.4.1 in Chapter 2.8. | Symbol: ![]() Signal word: Warning Hazard statement: Heating may cause a fire |
Type G | According to the results of tests in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part II and the application of the decision logic under 2.8.4.1 in Chapter 2.8. | No additional symbols, signal words, or hazard statements |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | The liquid ignites within 5 min when added to an inert carrier and exposed to air, or it ignites or chars a filter paper on contact with air within 5 min | Symbol: ![]() Signal word: Danger Hazard statement: Catches fire spontaneously if exposed to air |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | The solid ignites within 5 min of coming into contact with air | Symbol: ![]() Signal word: Danger Hazard statement: Catches fire spontaneously if exposed to air |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | A positive result is obtained in a test using a 25 mm sample cube at 140 °C | Symbol: ![]() Signal word: Danger Hazard statement: Self-heating; may catch fire |
2 | (a) A positive result is obtained in a test using a 100 mm sample cube at 140 °C and a negative result is obtained in a test using a 25 mm cube sample at 140 °C and the substance or mixture is to be packed in packages with a volume > 3 m3 ; or (b) A positive result is obtained in a test using a 100 mm sample cube at 140 °C and a negative result is obtained in a test using a 25 mm cube sample at 140 °C, a positive result is obtained in a test using a 100 mm cube sample at 120 °C and the substance or mixture is to be packed in packages with a volume > 450 liters; or (c) A positive result is obtained in a test using a 100 mm sample cube at 140 °C and a negative result is obtained in a test using a 25 mm cube sample at 140 °C and a positive result is obtained in a test using a 100 mm cube sample at 100 °C |
Symbol: ![]() Signal word: Warning Hazard statement: Self-heating in large quantities; may catch fire |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | Any substance or mixture which reacts vigorously with water at ambient temperatures and demonstrates generally a tendency for the gas produced to ignite spontaneously, or which reacts readily with water at ambient temperatures such that the rate of evolution of flammable gas is ≥ 10 liters per kilogram of substance over any one minute | Symbol: ![]() Signal word: Danger Hazard statement: In contact with water releases flammable gases which may ignite spontaneously |
2 | Any substance or mixture which reacts readily with water at ambient temperatures such that the maximum rate of evolution of flammable gas is ≥ 20 liters per kilogram of substance per hour, and which does not meet the criteria for Category 1 | Symbol: ![]() Signal word: Danger Hazard statement: In contact with water releases flammable gases |
3 | Any substance or mixture which reacts slowly with water at ambient temperatures such that the maximum rate of evolution of flammable gas is ≥ 1 litre per kilogram of substance per hour, and which does not meet the criteria for Categories 1 and 2 | Symbol: ![]() Signal word: Warning Hazard statement: In contact with water releases flammable gases |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | Any substance or mixture which, in the 1:1 mixture, by mass, of substance and cellulose tested, spontaneously ignites; or the mean pressure rise time of a 1:1 mixture, by mass, of substance and cellulose is less than that of a 1:1 mixture, by mass, of 50% perchloric acid and cellulose | Symbol: ![]() Signal word: Danger Hazard statement: May cause fire or explosion; strong oxidizer |
2 | Any substance or mixture which, in the 1:1 mixture, by mass, of substance and cellulose tested, exhibits a mean pressure rise time less than or equal to the mean pressure rise time of a 1:1 mixture, by mass, of 40% aqueous sodium chlorate solution and cellulose; and the criteria for Category 1 are not met | Symbol: ![]() Signal word: Danger Hazard statement: May intensify fire; oxidizer |
3 | Any substance or mixture which, in the 1:1 mixture, by mass, of substance and cellulose tested, exhibits a mean pressure rise time less than or equal to the mean pressure rise time of a 1:1 mixture, by mass, of 65% aqueous nitric acid and cellulose; and the criteria for Categories 1 and 2 are not met | Symbol: ![]() Signal word: Warning Hazard statement: May intensify fire; oxidizer |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | Any substance or mixture which, in the 4:1 or 1:1 sample-to-cellulose ratio (by mass) tested, exhibits a mean burning time less than the mean burning time of a 3:2 mixture, by mass, of potassium bromate and cellulose | Symbol: ![]() Signal word: Danger Hazard statement: May cause fire or explosion; strong oxidizer |
2 | Any substance or mixture which, in the 4:1 or 1:1 sample-to-cellulose ratio (by mass) tested, exhibits a mean burning time equal to or less than the mean burning time of a 2:3 mixture (by mass) of potassium bromate and cellulose, and the criteria for Category 1 are not met | Symbol: ![]() Signal word: Danger Hazard statement: May intensify fire; oxidizer |
3 | Any substance or mixture which, in the 4:1 or 1:1 sample-to-cellulose ratio (by mass) tested, exhibits a mean burning time equal to or less than the mean burning time of a 3:7 mixture (by mass) of potassium bromate and cellulose, and the criteria for Categories 1 and 2 are not met | Symbol: ![]() Signal word: Warning Hazard statement: May intensify fire; oxidizer |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
Type A | According to the results of test series A to H in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part II and the application of the decision logic under 2.15.4.1 in Chapter 2.15 | Symbol: ![]() Signal word: Danger Hazard statement: Heating may cause an explosion |
Type B | According to the results of test series A to H in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part II and the application of the decision logic under 2.15.4.1 in Chapter 2.15 | Symbols: ![]() ![]() Signal word: Danger Hazard statement: Heating may cause a fire or explosion |
Type C and D | According to the results of test series A to H in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part II and the application of the decision logic under 2.15.4.1 in Chapter 2.15 | Symbol: ![]() Signal word: Danger Hazard statement: Heating may cause a fire |
Type E and F | According to the results of test series A to H in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part II and the application of the decision logic under 2.15.4.1 in Chapter 2.15 | Symbol: ![]() Signal word: Warning Hazard statement: Heating may cause a fire |
Type G | According to the results of test series A to H in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part II and the application of the decision logic under 2.15.4.1 in Chapter 2.15 | There are no label elements allocated to this hazard category |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | Corrosion rate on either steel or aluminum surfaces exceeding 6.25 mm per year at a test temperature of 55 °C when tested on both materials | Symbol: ![]() Signal word: Warning Hazard statement: May be corrosive to metals |
Hazard category | Oral Criteria | Dermal Criteria | Inhalation Criteria | Additional Criteria | Hazard communication elements |
---|---|---|---|---|---|
1 | LD50 ≤ 5 mg/kg bodyweight | LD50 ≤ 50 mg/kg bodyweight | Lc50 ≤ 100 ppm (gas) Lc50 ≤ 0.5 mg/l (vapor) Lc50 ≤ 0.05 mg/l (dust, mist) |
N/A | Symbol: ![]() Signal word: Danger Hazard statement: Fatal if swallowed (oral). Fatal in contact with skin (dermal). Fatal if inhaled (gas, vapor, dust, mist). |
2 | LD50 > 5 but ≤ 50 mg/kg bodyweight | LD50 > 50 but ≤ 200 mg/kg bodyweight | Lc50 > 100 but ≤ 500 ppm (gas) Lc50 > 0.5 but ≤ 2.0 mg/l (vapor) Lc50 > 0.05 but ≤ 0.5 mg/l (dust, mist) |
N/A | Symbol: ![]() Signal word: Danger Hazard statement: Fatal if swallowed (oral). Fatal in contact with skin (dermal). Fatal if inhaled (gas, vapor, dust, mist). |
3 | LD50 > 50 but ≤ 300 mg/kg bodyweight | LD50 > 200 but ≤ 1000 mg/kg bodyweight | Lc50 > 500 but ≤ 2500 ppm (gas) Lc50 > 2.0 but ≤ 10.0 mg/l (vapor) Lc50 > 0.5 but ≤ 1.0 mg/l (dust, mist) |
N/A | Symbol: ![]() Signal word: Danger Hazard statement: Toxic if swallowed (oral). Toxic in contact with skin (dermal). Toxic if inhaled (gas, vapor, dust, mist). |
4 | LD50 > 300 but ≤ 2000 mg/kg bodyweight | LD50 > 1000 but ≤ 2000 mg/kg bodyweight | Lc50 > 2500 but ≤ 20000 ppm (gas) Lc50 > 10.0 but ≤ 20.0 mg/l (vapor) Lc50 > 1.0 but ≤ 5.0 mg/l (dust, mist) |
N/A | Symbol: ![]() Signal word: Warning Hazard statement: Harmful if swallowed (oral). Harmful in contact with skin (dermal). Harmful if inhaled (gas, vapor, dust, mist). |
5 | LD50 > 2000 but ≤ 5000 mg/kg | LD50 > 2000 but ≤ 5000 mg/kg | Lc50 in the equivalent range of the oral and dermal LD50 (ALL) (i.e. > 2000 but ≤ 5000 mg/kg bodyweight) | (1) Indication of significant toxicity effects in humans. (2) Any mortality at Category 4. (3) Significant clinical signs at Category 4. (4) Indication from other studies. |
There is no Symbol Signal word: Warning Hazard statement: May be harmful if swallowed (oral), May be harmful in contact with skin (dermal), May be harmful if inhaled (gas, vapor, dust, mist) |
Hazard category | Criteria for substances and tested mixtures | Criteria if bridging principles do not apply | Hazard communication elements |
---|---|---|---|
Corrosive Including subcategories A, B, and C; see Chapter 3.2, Table 3.2.1 | A. Human experience showing irreversible damage to the skin. B. Structure-activity relationship to a substance or mixture already classified as corrosive. C. pH extremes of ≤ 2 or ≥ 11.5 including acid/alkali reserve capacity. D. Positive results in a valid and accepted in vitro skin corrosion test. E. Animal experience or test data that indicate that the substance/mixture causes irreversible damage to the skin following exposure of up to 4 h (see Table 3.2.1). Note that if data for the complete mixture are not available, apply bridging principles (see 3.2.3.2) |
A. For mixtures where the concentrations of the ingredients can be added, classify in Category 1 if the sum of the concentrations of Category 1 ingredients is ≥ 5%. B. For mixtures where the concentrations of the ingredients cannot be added, classify in Category 1 if the mixture contains ≥ 1% of a Category 1 ingredient (see 3.2.3.3.4). |
Symbol: ![]() Signal word: Danger Hazard statement: Causes severe skin burns and eye damage |
Irritant (applies to all authorities) | A. Human experience or data showing reversible damage to the skin following exposure of up to 4 hours. B. Structure-activity relationship to a substance or mixture already classified as an irritant. C. Positive results in a valid and accepted in vitro skin irritation test. D. Animal experience or test data that indicate that the substance/mixture causes reversible damage to the skin following exposure of up to 4 h, mean value of ≥ 2.3 ≤ 4.0 for erythema/eschar or for oedema, or inflammation that persists to the end of the observation period, in 2 of 3 tested animals (Table 3.2.2). Note that if data for the complete mixture are not available, apply bridging principles (see 3.2.3.2). |
A. For mixtures where the concentrations of the ingredients can be added, classify in Category 2: If the sum of concentrations of Category 1 ingredients is ≥ 1% but < 5%; or If the sum of concentrations of Category 2 ingredients is ≥ 10%; or If [(10 × sum of concentrations of Category 1 ingredients) + (sum of concentrations of Category 2 ingredients)] is ≥ 10%; B. For mixtures where the concentrations of the ingredients cannot be added, classify in Category 2 if the mixture contains ≥ 3% of a Category 2 ingredient (see 3.2.3.3.4). |
Symbol: ![]() Signal word: Warning Hazard statement: Causes skin irritation |
Mild irritant (applies to some authorities) | Animal experience or test data that indicates that the substance/mixture causes reversible damage to the skin following exposure of up to 4 h, mean value of ≥ 1.5 < 2.3 for erythema/eschar in 2 of 3 tested animals (See Table 3.2.2). Note that if data for the complete mixture are not available, apply bridging principles (see 3.2.3.2). |
A. For mixtures where the concentrations of the ingredients can be added, classify in Category 3: If the sum of concentrations of Category 2 ingredients is ≥ 1% but < 10%; or If the sum of the concentrations of Category 3 ingredients is ≥ 10%; or If [(10 × sum of concentrations of Category 1 ingredients) + (sum of concentrations of Category 2 ingredients)] is ≥ 1% but < 10%; or If [(10 × sum of concentrations of Category 1 ingredients) + (sum of concentrations of Category 2 ingredients) + (sum of concentrations of Category 3 ingredients)] is ≥ 10%; B. For mixtures where the concentrations of the ingredients cannot be added, classify in Category if the mixture contains ≥ 3% of a Category 3 ingredient (see 3.2.3.3.4). |
The is no symbol Signal word: Warning Hazard statement: Causes mild skin irritation |
Hazard category | Criteria for substances and tested mixtures | Criteria if bridging principles do not apply | Hazard communication elements |
---|---|---|---|
1 Irreversible effects | A. Classification as corrosive to skin. B. Human experience or data showing damage to the eye which is not fully reversible within 21 days. C. Structure-activity relationship to a substance or mixture already classified as corrosive. D. pH extremes of ≤ 2 and ≥ 11.5 including buffering capacity. E. Positive results in a valid and accepted in vitro test to assess serious damage to eyes F. Animal experience or test data that the substance or mixture produces... 1. In at least one animal, effects on the cornea, iris, or conjunctiva that are not expected to reverse or have not reversed; or 2. In at least 2 of 3 tested animals, a positive response of corneal opacity ≥ 3 and/or iritis > 1.5 (see Table 3.3.1). Note that if data for the complete mixture are not available, apply bridging principles (see 3.3.3.2). |
A. For mixtures where the concentrations of the ingredients can be added, classify in Category 1 if the sum of concentrations of skin and/or eye Category 1 ingredients is ≥ 3%. B. For mixtures where the concentrations of the ingredients cannot be added, classify in Category 1 if the mixture contains ≥ 1% of a skin and/or eye Category 1 ingredient(s) (see 3.3.3.3.4). |
Symbol: ![]() Signal word: Danger Hazard statement: Causes serious eye damage |
2A Irritant | A. Classification as severe skin irritant. B. Human experience or data showing production of changes in the eye which are fully reversible within 21 days. C. Structure-activity relationship to a substance or mixture already classified as an eye irritant D. Positive results in a valid and accepted in vitro eye irritation test. E. Animal experience or test data that indicate that the substance/mixture produces a positive response in at least 2 of 3 tested animals of: corneal opacity ≥ 1, iritis ≥ 1, or conjunctival edema (chemosis) ≥ 2 (Table 3.3.2). Note that if data for the complete mixture are not available, apply bridging principles (see 3.3.3.2). |
A. Mixtures where the concentrations of the ingredients can be added, classify in Category 2A: 1. If the sum of the concentrations of skin and/or eye Category 1 ingredients is ≥ 1% but < 3%; or 2. If the sum of the concentrations of eye Category 2/2A ingredients is ≥ 10%; or 3. If [(10 × sum of concentrations of skin and/or eye Category 1 ingredients) + (sum of concentrations of eye Category 2A/2B ingredients)] is ≥ 10%; B. Mixtures where the concentrations of the ingredients cannot be added, classify in Category 2A if the mixture contains ≥ 3% of an eye Category 2 ingredient (see 3.3.3.3.4) |
Symbol: ![]() Signal word: Warning Hazard statement: Causes serious eye irritation |
2B Mild Irritant | A. Human experience or data showing production of mild eye irritation. B. Animal experience or test data that indicate that the lesions are fully reversible within 7 days (see Table 3.3.2). Note that if data for the complete mixture are not available, apply bridging principles (see 3.3.3.2). |
A. Mixtures where the concentrations of the ingredients can be added, classify in Category 2B: 1. if the sum of the concentrations of skin and/or eye Category 1 ingredients is ≥ 1% but < 3%; or 2. if the sum of the concentrations of eye Category 2 ingredients is ≥ 10%; or 3. if [(10 × sum of concentrations of skin and/or eye Category 1 ingredients) + (sum of concentrations of eye Category 2 ingredients)] is ≥ 10%. B. Mixtures where the concentrations of the ingredients cannot be added, classify in Category 2B if mixture contains ≥ 3% of an eye Category 2 ingredient (see 3.3.3.3.4) |
There is no symbol Signal word: Warning Hazard statement: Causes eye irritation |
Hazard category | Criteria for substances and tested mixtures | Criteria if bridging principles do not apply | Hazard communication elements |
---|---|---|---|
1 | A. If there is evidence in humans that the substance can lead to specific respiratory hypersensitivity, and/or B. If there are positive results from an appropriate animal test. Note that if data for the complete mixture are not available, apply bridging principles (see 3.4.3.2). |
Classify the mixture as a respiratory sensitizer if it contains at least one ingredient classified as respiratory sensitizer at the following concentrations... A. Solids or liquids: 1. ≥ 0.1% w/w (see note to Table 3.4.5); or 2. ≥ 1.0% w/w; B. Gases: 1. ≥ 0.1% v/v (see note to Table 3.4.5); or 2. ≥ 0.2% v/v |
Symbol: ![]() Signal word: Danger Hazard statement: May cause allergy or asthmatic symptoms or breathing difficulties if inhaled |
1A (where data are sufficient and where required by a competent authority) | Showing a high frequency of occurrence in humans; or a probability of occurrence of a high sensitization rate in humans based on animal or other tests. Severity of reaction may also be considered. Note that if data for the complete mixture are not available, apply bridging principles (see 3.4.3.2). |
Classify the mixture as a respiratory sensitizer if it contains at least one ingredient classified as sub-category 1A at the following concentrations... A. Solids or liquids: ≥ 0.1% w/w B. Gases: ≥ 0.1% v/v |
Symbol: ![]() Signal word: Danger Hazard statement: May cause allergy or asthmatic symptoms or breathing difficulties if inhaled |
1B (where data are sufficient and where required by a competent authority) | Showing a low to moderate frequency of occurrence in humans; or a probability of occurrence of a low to moderate sensitization rate in humans based on animal or other tests. Severity of reaction may also be considered. Note that if data for the complete mixture are not available, apply bridging principles (see 3.4.3.2). |
Classify the mixture as a respiratory sensitizer if it contains at least one ingredient classified as sub-category 1B at the following concentrations... A. Solids or liquids: ≥ 1% w/w B. Gases: ≥ 0.2% v/v |
Symbol: ![]() Signal word: Danger Hazard statement: May cause allergy or asthmatic symptoms or breathing difficulties if inhaled |
Hazard category | Criteria for substances and tested mixtures | Criteria if bridging principles do not apply | Hazard communication elements |
---|---|---|---|
1 | A. If there is evidence in humans that the individual substance can lead to sensitization by skin contact in a substantial number of persons, or B. If there are positive results from an appropriate animal test. Note that if data for the complete mixture are not available, apply bridging principles (see 3.4.3.2). |
Classify the mixture as a skin sensitizer if it contains at least one ingredient classified as a skin sensitizer at the following concentrations... A. ≥ 0.1% (solid/liquid/gas) see note to Table 3.4.5; or B. ≥ 1.0% (solid/liquid/gas). |
Symbol: ![]() Signal word: Warning Hazard statement: May cause an allergic skin reaction |
1A (where data are sufficient and where required by a competent authority) | Showing a high frequency of occurrence in humans and/or a high potency in animals, which can be presumed to have the potential to produce significant sensitization in humans. Severity of reaction may also be considered. Note that if data for the complete mixture are not available, apply bridging principles (see 3.4.3.2). |
Classify the mixture as a skin sensitizer if it contains at least one ingredient classified as sub-category 1A at a concentration ≥ 0.1% | Symbol: ![]() Signal word: Warning Hazard statement: May cause an allergic skin reaction |
1B (where data are sufficient and where required by a competent authority) | showing a low to moderate frequency of occurrence in humans and/or a low to moderate potency in animals, which can be presumed to have the potential to produce sensitization in humans. Note that if data for the complete mixture are not available, apply bridging principles (see 3.4.3.2). |
Classify the mixture as a skin sensitizer if it contains at least one ingredient classified as sub-category 1B at a concentration ≥ 1% | Symbol: ![]() Signal word: Warning Hazard statement: May cause an allergic skin reaction |
Hazard category | Criteria for substances and tested mixtures (see criteria in 3.5.2) | Criteria if bridging principles do not apply | Hazard communication elements |
---|---|---|---|
1 (Both 1A and 1B) | A. Known to induce heritable mutations in germ cells of humans; or B. Regarded as if they induce heritable mutations in the germ cells of humans. Note that if data for the complete mixture are not available, apply bridging principles (see 3.5.3.2). |
Classify the mixture in Category 1 if it contains at least one ingredient classified in Category 1 at a concentration ≥ 0.1 % | Symbol: ![]() Signal word: Danger Hazard statement: May cause genetic defects (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard) |
2 | That which cause concern for humans owing to the possibility that they may induce heritable mutations in the germ cells of humans. Note that if data for the complete mixture are not available, apply bridging principles (see 3.5.3.2). |
Classify the mixture in Category 2 if it contains at least one ingredient classified in Category 2 at a concentration ≥ 1.0 % | Symbol: ![]() Signal word: Warning Hazard statement: Suspected of causing genetic defects (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard) |
Hazard category | Criteria for substances and tested mixtures (see criteria in 3.6.2) | Criteria if bridging principles do not apply | Hazard communication elements |
---|---|---|---|
1 (Both 1A and 1B) | A. Known to have carcinogenic potential for humans. B. Presumed to have carcinogenic potential for humans. Note that if data for the complete mixture are not available, apply bridging principles (see 3.6.3.2). |
Classify the mixture in Category 1 if it contains at least one ingredient classified in Category 1 at a concentration ≥ 0.1 % | Symbol: ![]() Signal word: Danger Hazard statement: May cause cancer (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard) |
2 | Suspected human carcinogens. Note that if data for the complete mixture are not available, apply bridging principles (see 3.6.3.2). |
Classify the mixture in Category 2 if it contains at least one ingredient classified in Category 2 at the following concentrations... A. ≥ 0.1% (see 3.6.3.3 and note 1 to Table 3.6.1); or B. ≥ 1.0 % (see 3.6.3.3 and note 2 to Table 3.6.1). |
Symbol: ![]() Signal word: Warning Hazard statement: Suspected of causing cancer (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard). Note that while some authorities will choose to label according to this provision, others may not. |
Hazard category | Criteria for substances and tested mixtures (see criteria in 3.7.2) | Criteria if bridging principles do not apply | Hazard communication elements |
---|---|---|---|
1 (Both 1A and 1B) | A. Known human reproductive toxicant; or B. Presumed human reproductive toxicant. Note that if data for the complete mixture are not available, apply bridging principles (see 3.7.3.2). |
Classify the mixture in Category 1 if it contains at least one ingredient classified in Category 1 at the following concentrations... A. ≥ 0.1% (see 3.7.3.3 and note 1 to Table 3.7.1); or B. ≥ 0.3 % (see 3.7.3.3 and note 2 to Table 3.7.1). |
Symbol: ![]() Signal word: Danger Hazard statement: May damage fertility or the unborn child (state specific effect if known) (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard) |
2 | Suspected human reproductive toxicants. Note that if data for the complete mixture are not available, apply bridging principles (see 3.7.3.2). |
Classify the mixture in Category 2 if it contains at least one ingredient classified in Category 2 at the following concentrations... A. ≥ 0.1 % (see 3.7.3.3 and note 3 to Table 3.7.1); or B. ≥ 3.0 % (see 3.7.3.3 and note 4 to Table 3.7.1). |
Symbol: ![]() Signal word: Warning Hazard statement: Suspected of damaging fertility or the unborn child (state specific effect if known) (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard) |
Additional category for effects on or via lactation | Substances or mixtures which cause concern for the health of breast-fed children. Note that if data for the complete mixture are not available, apply bridging principles (see 3.7.3.2). |
Classify the mixture in this category if it contains at least one ingredient classified in this category at the following concentrations... A. ≥ 0.1 % (see 3.7.3.3 and note 1 to Table 3.7.1); or B. ≥ 0.3 % (see 3.7.3.3 and note 2 to Table 3.7.1). |
There is no symbol or signal word. Hazard statement: May cause harm to breast-fed children |
Hazard category | Criteria for substances and tested mixtures (see criteria in 3.8.2) | Criteria if bridging principles do not apply | Hazard communication elements |
---|---|---|---|
1 | Reliable evidence on the substance or mixture (including bridging principles) of an adverse effect on specific organs or systems in humans or animals. May use guidance values in Table 3.8.1, Category 1 criteria as part of weight of evidence evaluation. May be named for specific organ/system affected. Note that if data for the complete mixture are not available, apply bridging principles (see 3.8.3.3). |
Classify the mixture in Category 1 if it contains at least one ingredient classified in Category 1 at the following concentrations... A. ≥ 1.0% (see 3.8.3.4 and note 1 to Table 3.8.2); or B. ≥ 10% (see 3.8.3.4 and note 2 to Table 3.8.2) |
Symbol: ![]() Signal word: Danger Hazard statement: Causes damage to organs (or state all organs affected, if known) (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard) |
2 | Evidence on the substance or mixture (including bridging principles) of an adverse effect on specific organs or systems from animal studies or humans considering weight of evidence and guidance values in Table 3.8.1, Category 2 criteria. May be named for specific organ/system affected. Note that if data for the complete mixture are not available, apply bridging principles (see 3.8.3.3). |
A. Classify the mixture in Category 2 if it contains at least one ingredient classified in Category 1 at a concentration ≥ 1 but < 10%; (see 3.8.3.4 and note 3 to table 3.8.2) B. Classify the mixture in Category 2 if it contains at least one ingredient classified in Category 2 at the following concentrations... 1. ≥ 1% (see 3.8.3.4 and note 4 to Table 3.8.2); or 2. ≥ 10% (see 3.8.3.4 and note 5 to Table 3.8.2). |
Symbol: ![]() Signal word: Warning Hazard statement: May cause damage to organs (or state all organs affected, if known) (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard) |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
3 | A. (Respiratory tract irritation) Evidence on the substance or mixture of transient irritant effects on respiratory tract in humans; or B. (Narcotic effects) Evidence on the substance or mixture of transient narcotic effects from animal studies and in humans. |
Symbol: ![]() Signal word: Warning Hazard statement: Respiratory tract irritation) May cause respiratory irritation, or (Narcotic effects) May cause drowsiness or dizziness |
Hazard category | Criteria for substances and tested mixtures (see criteria in 3.9.2) | Criteria if bridging principles do not apply | Hazard communication elements |
---|---|---|---|
1 | Reliable evidence on the substance or mixture (including bridging principles) of an adverse effect on specific organs or systems in humans or animals. May use guidance values in Table 3.9.1 as part of weight of evidence evaluation. May be named for specific organ/system. Note that if data for the complete mixture are not available, apply bridging principles (see 3.9.3.3). |
Classify the mixture in Category 1 if it contains at least one ingredient classified in Category 1 at the following concentrations... A. ≥ 1.0% (see 3.9.3.4 and note 1 to Table 3.9.3); or B. ≥ 10% (see 3.9.3.4 and note 2 to Table 3.9.3). |
Symbol: ![]() Signal word: Danger Hazard statement: Causes damage to organs (state all organs affected, if known) through prolonged or repeated exposure (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard). |
2 | Evidence on the substance or mixture (including bridging principles) of an adverse effect on specific organs or systems from animal studies or humans considering weight of evidence and guidance values in Table 3.9.2. May be named for specific organ/system. Note that if data for the complete mixture are not available, apply bridging principles (see 3.9.3.3). |
A. Classify the mixture in Category 2 if it contains at least one ingredient classified in Category 1 at a concentration ≥ 1.0 but < 10% (see 3.9.3.4 and note 3 to table 3.9.3). B. Classify the mixture in Category 2 if it contains at least one ingredient classified in Category 2 at the following concentrations... 1. ≥ 1.0% (see 3.9.3.4 and note 4 to Table 3.9.3); or 2. ≥ 10% (see 3.9.3.4 and note 5 to Table 3.9.3). |
Symbol: ![]() Signal word: Warning Hazard statement: May cause damage to organs (state all organs affected, if known) through prolonged or repeated exposure (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard). |
Hazard category | Criteria for substances and tested mixtures | Criteria if bridging principles do not apply | Hazard communication elements |
---|---|---|---|
1 | A. Practical experience from reliable and good quality human evidence showing human aspiration toxicity including chemical pneumonia, varying degree of pulmonary injury, or death following aspiration. B. Hydrocarbons with a kinematic viscosity ≤ 20.5mm2/s, measured at 40°C. Note that if data for the complete mixture are not available, apply bridging principles (see 3.10.3.2). |
A. Classify the mixture in Category 1 if it contains at least one ingredient classified in Category 1 and having a kinematic viscosity ≤ 20.5 mm2/s measured at 40°C, at a concentration ≥ 10%; or B. For mixtures which separate into two or more distinct layers, if at least one layer contains one ingredient classified in Category 1 and having a kinematic viscosity ≤ 20.5mm2/s measured at 40°C, at a concentration ≥ 10%. |
Symbol: ![]() Signal word: Danger Hazard statement: May be fatal if swallowed and enters airways |
2 | Substances and mixtures other than those classified in Category 1 which, on the basis of animal studies and expert judgment are presumed to cause human aspiration toxicity and have a kinematic viscosity ≤ 14mm2/s, measured at 40°C. Note that if data for the complete mixture are not available, apply bridging principles (see 3.10.3.2). |
A. Classify the mixture in Category 2 if it contains at least one ingredient classified in Category 2 and having a kinematic viscosity ≤ 14mm2/s measured at 40°C, at a concentration ≥ 10%; or B. For mixtures which separate into two or more distinct layers, if at least one layer contains one ingredient classified in Category 2 and having a kinematic viscosity ≤ 14 mm2/s measured at 40°C, at a concentration ≥ 10%. |
Symbol: ![]() Signal word: Warning Hazard statement: May be harmful if swallowed and enters airways |
Hazard category | Criteria for substances and tested mixtures | Criteria if bridging principles do not apply | Criteria for mixtures with no usable information for one or more relevant ingredients | Hazard communication elements |
---|---|---|---|---|
1 | L(E)C50 ≤ 1mg/l where L(E)C50 is either 96hr Lc50 (for fish), 48hr EC Lc50 (for crustacea) or 72 or 96hr ErC550 (for algae or other aquatic plants). Note that if data for the complete mixture are not available, apply bridging principles (see 4.1.3.4). |
A. For mixtures with classified ingredients, apply the summation method (see 4.1.3.5.5) and classify in Acute 1 if: [(Sum of concentrations of Acute 1 ingredients) × M] is ≥ 25% where M is a multiplying factor (see 4.1.3.5.5.5). B. For mixtures with tested ingredients, apply the additivity formula (see 4.1.3.5.2 and 4.1.3.5.3) and classify in Acute 1 if: L(E)C50 ≤ 1mg/l C. For mixtures with both classified and tested ingredients, apply the combined additivity formula and summation method (see 4.1.3.5.2 to 4.1.3.5.5.3) and classify in Acute 1 if: [(Sum of concentrations of Acute 1 ingredients) × M] is ≥ 25% |
Classify using the available information and add the statement: “X% of the mixture consists of ingredient(s) of unknown hazards to the aquatic environment” | Symbol: ![]() Signal word: Warning Hazard statement: Very toxic to aquatic life |
2 | L(E)C50 >1 mg/l but ≤ 10 mg/l where L(E)C50 is either 96hr Lc50 (for fish), 48hr EC Lc50 (for crustacea) or 72 or 96hr ErC550 (for algae or other aquatic plants). Note that if data for the complete mixture are not available, apply bridging principles (see 4.1.3.4). |
A. For mixtures with classified ingredients, apply the summation method (see 4.1.3.5.5) and classify in Acute 2 if: [(Sum of concentrations of Acute 1 ingredients × M × 10) + (Sum of concentrations of Acute 2 ingredients)] is ≥ 25% where M is a multiplying factor (see 4.1.3.5.5.5). B. For mixtures with tested ingredients, apply the additivity formula (see 4.1.3.5.2 and 4.1.3.5.3) and classify in Acute 2 if: L(E)C50 >1 mg/l but ≤ 10 mg/l. C. For mixtures with both classified and tested ingredients, apply the combined additivity formula and summation method (see 4.1.3.5.2 to 4.1.3.5.5.3) and classify in Acute 2 if: [(Sum of concentrations of Acute 1 ingredients × M × 10) + (Sum of concentrations of Acute 2 ingredients)] is ≥ 25% |
Classify using the available information and add the statement: “X% of the mixture consists of ingredient(s) of unknown hazards to the aquatic environment” | There is no symbol or signal word. Hazard statement: Toxic to aquatic life |
3 | L(E)C50 > 10 mg/l but ≤ 100 mg/l where L(E)C50 is either 96hr Lc50 (for fish), 48hr EC Lc50 (for crustacea) or 72 or 96hr ErC550 (for algae or other aquatic plants) Note that if data for the complete mixture are not available, apply bridging principles (see 4.1.3.4). |
A. For mixtures with classified ingredients, apply the summation method (see 4.1.3.5.5) and classify in Acute 3 if: [(Sum of concentrations of Acute 1 ingredients × M × 100) + (Sum of concentrations of Acute 2 ingredients × 10) + (Sum of concentrations of Acute 3 ingredients)] is ≥ 25% where M is a multiplying factor (see 4.1.3.5.5.5) B. For mixtures with tested ingredients, apply the additivity formula (see 4.1.3.5.2 and 4.1.3.5.3) and classify in Acute 3 if: L(E)C50 > 10 mg/l but ≤ 100 mg/l C. For mixtures with both classified and tested ingredients, apply the combined additivity formula and summation method (see 4.1.3.5.2 to 4.1.3.5.5.3) and classify in Acute 3 if:[(Sum of concentrations of Acute 1 ingredients × M × 100) + (Sum of concentrations of Acute 2 ingredients × 10) + (Sum of concentrations of Acute 3 ingredients)] is ≥ 25% |
Classify using the available information and add the statement: “X% of the mixture consists of ingredient(s) of unknown hazards to the aquatic environment” | There is no symbol or signal word. Hazard statement: Harmful to aquatic life |
Hazard category | Criteria for substances that are rapidly degradable | Criteria for substances that are non-rapidly degradable | Criteria if bridging principles do not apply | Criteria for mixtures with no usable information for one or more relevant ingredients | Hazard communication elements |
---|---|---|---|---|---|
1 | A. NOEC ≤ 0.01 mg/l; or, if absent B. L(E)C50 ≤ 1 mg/l, and BCF ≥ 500 (or if absent log Kow ≥ 4) Note that if data for the complete mixture are not available, apply bridging principles (see 4.1.3.4). |
A. NOEC ≤ 0.1 mg/l; or if absent B. L(E)C50 ≤ 1 mg/l |
Classify in Chronic 1 if: [(Sum of concentrations of Chronic 1 ingredients) × M] is ≥ 25% where M is a multiplying factor (see 4.1.3.5.5.5). | Classify using the available information and add the statement: “×% of the mixture consists of ingredient(s) of unknown hazards to the aquatic environment”. | Symbol: ![]() Signal word: Warning Hazard statement: Very toxic to aquatic life with long lasting effects |
2 | A. 0.01 < NOEC ≤ 0.1 mg/l; or, if absent B. 1 mg/l < L(E)C50 ≤ 10 mg/l and BCF ≥ 500 (or if absent log Kow ≥ 4) Note that if data for the complete mixture are not available, apply bridging principles (see 4.1.3.4). |
A. 0.1 < NOEC ≤ 1 mg/l; or if absent B. 1 mg/l < L(E)C50 ≤ 10 mg/l |
Classify in Chronic 2 if: [(Sum of concentrations of Chronic 1 ingredients × M × 10) + (Sum of concentrations of Chronic 2 ingredients)] is ≥ 25% where M is a multiplying factor (see 4.1.3.5.5.5) | Classify using the available information and add the statement: “×% of the mixture consists of ingredient(s) of unknown hazards to the aquatic environment”. | Symbol: ![]() Hazard statement: Toxic to aquatic life with long lasting effects |
3 | A. 0.1 mg/l < NOEC ≤ 1 mg/l; or, if absent B. 10 mg/l 50 ≤ 100 mg/l and BCF ≥ 500 (or, if absent, log Kow ≥ 4). Note that if data for the complete mixture are not available, apply bridging principles (see 4.1.3.4). |
10 mg/l 50 ≤ 100 mg/l | Classify in Chronic 3 if: [(Sum of concentrations of Chronic 1 ingredients × M × 100) + (Sum of concentrations of Chronic 2 ingredients × 10) + (Sum of concentrations of Chronic 3 ingredients)] is ≥ 25% where M is a multiplying factor (see 4.1.3.5.5.5). | Classify using the available information and add the statement: “×% of the mixture consists of ingredient(s) of unknown hazards to the aquatic environment”. | There is no symbol or signal word. Hazard statement: Harmful to aquatic life with long lasting effect |
Hazard category | Criteria for substances and tested mixtures | Criteria if bridging principles do not apply | Criteria for mixtures with no usable information for one or more relevant ingredients | Hazard communication elements |
---|---|---|---|---|
4 | A. poorly soluble and no acute toxicity is observed up the water solubility; B. Lack the potential to rapidly biodegrade and have the potential to bioaccumulate (BCF ≥ 500 or, if absent, log Kow ≥ 4); unless Chronic NOECs > 1 mg/l; Note that if data for the complete mixture are not available, apply bridging principles (see 4.1.3.4). |
Classify in Chronic 4 if: [(Sum of concentrations of Chronic 1 ingredients) + (Sum of concentrations of Chronic 2 ingredients) + (Sum of concentrations of Chronic 3 ingredients) + (Sum of concentrations of Chronic 4 ingredients)] is ≥ 25%. | Classify using the available information and add the statement: “×% of the mixture consists of ingredient(s) of unknown hazards to the aquatic environment”. | There is no symbol or signal word. Hazard statement: May cause long lasting harmful effects to aquatic life |
Hazard category | Criteria | Hazard communication elements |
---|---|---|
1 | 1. For substances - Any of the controlled substances listed in the Annexes to the Montreal Protocol. 2. For mixtures - Any mixture containing at least one ingredient listed in the Annexes to the Montreal Protocol, at a concentration ≥ 0.1%. |
Symbol: ![]() Signal word: Warning Hazard statement: Harms public health and the environment by destroying ozone in the upper atmosphere |